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Nimotop

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Contents

Common use

Nimotop (nimodipine) is a calcium channel blocker used to reduce the risk of brain damage caused by vasospasm after subarachnoid hemorrhage (SAH) - a type of bleeding around the brain.

It works by relaxing and widening the blood vessels in the brain, helping to improve blood flow and oxygen delivery to affected areas.

Nimotop is not used for treating high blood presure or general heart problems - it is specific to brain-related circulation issues.

Dosage and direction

Nimotop is usually taken as 60 mg every 4 hours for 21 days, starting within 96 hours of the SAH event.

Take the capsules by mouth on an empty stomach or 1 hour before or 2 hours after meals. Swallow whole with a glass of water. Do not chew or crush.

If you are receiving this medication via tube (for example, nasogastric), special handling may be required by healthcare providers.

Precautions

Before using Nimotop, tell your doctor if you have:
Liver disease
Low blood pressure
History of fainting
Allergy to calcium channel blockers

Avoid grapefruit or grapefruit juice while taking this medicine, as it can increase blood levels of nimodipine and lead to unwanted effects.

Contraindications

Do not use Nimotop if you:
Are allergic to nimodipine or similar medications
Have significant hypotension
Are using strong CYP3A4 inhibitors like ketoconazole or clarithromycin

This medication is not for use during pregnancy unless clearly needed. Discuss the risks with your doctor.

Possible side effects

Common side effects may include:
Dizziness or lightheadedness
Headache
Slow heartbeat
Nausea

Serious side effects (rare):
Fainting
Swelling of hands/ankles
Irregular heartbeat
Yellowing of skin or eyes (liver problems)

Tell your doctor if any side effects seem unusual or bothersome.

Drug interactions

Avoid taking Nimotop with:
Grapefruit products
CYP3A4 inhibitors (e.g., ritonavir, erythromycin)
Antifungal meds (ketoconazole, itraconazole)
Antiseizure drugs like phenytoin or carbamazepine

Also, do not use Nimotop with intravenous medications due to serious risk of hypotension.

Missed dose

If you miss a dose, take it as soon as you remember. If it's near the time of your next dose, skip the missed one. Don't take double doses.

Overdose

Overdose symptoms include very low blood pressure, fast or slow heartbeat, fainting, and confusion. Get emergncy medical help if overdose is suspected.

Storage

Store at room temperature (68F-77F / 20C-25C), protected from light and moisture. Do not freeze. Keep out of reach of children.

U.S. Sale and Prescription Policy

Nimotop is a prescription-only medication in the United States and is FDA-approved specifically for reducing neurological damage after a subarachnoid hemorrhage.

It must be prescribed and supervised by a licensed healthcare provider, especially in hospital settings or during recovery from brain injury.

It is not available for over-the-counter purchase. Buying or using Nimotop without prescription in the U.S. is both unsafe and illegal.

Disclaimer

This information is provided for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor for guidance regarding any medication.