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Contents
Common use
Antabuse (disulfiram) is a medication used in the treatment of chronic alcoholism. It acts as a deterrent to drinking alcohol by interfering with the way the body processes it. When alcohol is consumed while taking Antabuse, it causes unpleasant reactions like flushing, nausea, vomiting, headache, and rapid heartbeat.
It is not a cure for alcoholism but is used as a part of a full treatment plan including therapy and support.
Dosage and direction
Take Antabuse orally once a day, usually in the morning. Your doctor may start you on a lower dose (e.g. 250 mg) and adjust as needed.
You must not drink any alcohol (even small amounts from sauces or medicines) for at least 12 hours before starting Antabuse. Effects can last up to 2 weeks after the last dose.
Take with or without food. Swallow tablets whole with water.
Precautions
Before starting Antabuse, tell your doctor if you have:
Liver disease
Heart or blood vessel disorders
Diabetes
Epilepsy or seizures
Mental illness
Avoid products that may contain hidden alcohol, including:
Aftershaves and perfumes
Cough syrups
Fermented vinegars or sauces
Antabuse may cause drowziness - do not drive or operate heavy machinery until you know how it affects you.
Contraindications
Do not take Antabuse if you:
Are currently drinking or have recently consumed alcohol
Have severe heart disease or psychosis
Are allergic to disulfiram
Are pregnant or breastfeeding without medical advice
Possible side effects
Common side effects may include:
Fatigue or sleepiness
Acne or rash
Metallic or garlic-like taste in mouth
More serious (rare):
Liver damage (yellowing of skin or eyes)
Nerve pain, tingling or numbness
Mood changes or confusion
Seek medical help if you experience seizures, chest pain, or any severe reaction after alcohol consumption.
Drug interactions
Antabuse may interact with:
Metronidazole (can cause psychotic reactions)
Warfarin (may increase bleeding risk)
Phenytoin or isoniazid
Theophylline
Always inform your doctor of all medications you are taking before starting Antabuse.
Missed dose
If you miss a dose, take it as soon as possible. If it is almost time for the next dose, skip the missed one. Do not take two doses at once.
Overdose
Overdose symptoms may include nausea, vomiting, dizzyness, low blood pressure, or seizures. Contact emergency services if overdose is suspected.
Storage
Store Antabuse tablets at room temperature (68F-77F / 20C-25C) away from moisture, light, and heat. Keep out of reach of children and pets.
U.S. Sale and Prescription Policy
In the United States, Antabuse is an FDA-approved prescription medication. It is available only with a valid prescription and must be used under medical supervision.
The use of Antabuse without proper guidance can lead to severe reactions and is considered unsafe. U.S. law prohibits the sale of disulfiram without a prescription from a licensed healthcare provider.
It is important to obtain Antabuse only from certified pharmacies to ensure authenticity and proper dosage.
Disclaimer
This content is for informational purposes only and not a substitute for professional medical advice. Always consult your doctor or healthcare provider before starting or stopping any medication.