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Contents
Common use
Allopurinol is a xanthine oxidase inhibitor that helps lower uric acid levels in the blood and urine. It is mainly prescribed for patients suffering from gout, kidney stones, and uric acid build-up caused by cancer treatmants.
It doesn't treat acute gout attacks, but helps prevent them by keeping uric acid levels under control over time.
Dosage and direction
Take Allopurinol by mouth, usually once or twice daily after meals with a full glass of water. The dosage is based on your medical condition and response to treatment.
Drink plenty of fluids unless otherwise directed. Do not stop taking allopurinol even if you feel well. It may take several weeks before you see the full benefits.
Your doctor may start with a low dose and gradually increase it to avoid side effects.
Precautions
Before taking Allopurinol, tell your doctor if you have:
Liver disease
Kidney disease
Diabetes
High blood pressure
Tell your doctor if you are pregnant or brestfeeding.
Severe skin reactions are rare but possible, especially in Asian patients with the HLA-B5801 gene variant.
Contraindications
Do not use Allopurinol if you are allergic to it or to similar medications. It should not be used during an acute gout attack.
Avoid alcohol and high-purine foods, which can increase uric acid levels and worsen symptoms.
Possible side effects
Common side effects:
Nausea
Diarrhea
Rash
Drowsyness
Serious side effects (rare):
Severe skin reactions (Stevens-Johnson syndrome)
Liver function changes
Blood in urine
Numbness or tingling in arms or legs
Contact your doctor right away if you experience any unusual symptoms.
Drug interactions
Inform your doctor of all medications you use, especially:
Azathioprine
Mercaptopurine
Ampicillin or amoxicillin
Blood thinners (like warfarin)
Some antibiotics and cancer drugs may increase risk of toxicity when used with allopurinol.
Missed dose
If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Don't double up the dose.
Overdose
In case of overdose, symptoms may include nausea, dizziness, or severe skin reaction. Seek emergncy medical attention right away.
Storage
Store Allopurinol at room temperature (68F-77F / 20C-25C), away from moisture and heat. Keep the bottle tightly closed and out of reach of children and pets.
U.S. Sale and Prescription Policy
Allopurinol is an FDA-approved prescription medication in the United States. It is not available over the counter and must be prescribed by a licensed medical provider.
Proper medical supervision is required, especially in long-term use, to monitor kidney and liver function. Routine blood tests may be necessary to ensure safe treatment.
Buying Allopurinol without a valid U.S. prescription may be illegal and unsafe. Only purchase from certified U.S.-based pharmacies.
Disclaimer
This information is provided for educational purposes only and should not replace consultation with a licensed physician. Always follow your doctor's instructions and read the patient leaflet before use.